Have You Met Rutgers-Newark?
The research being conducted by this Rutgers Board of Governors Professor Dr. Frank Jordan has significant implications for discovering chemical processes that underlie critical human reactions. And those discoveries would be crucial to developing new medications.
Jordan’s research uses the major tools of structural biology -- nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry, and X-ray crystallography -- to map out structures of proteins, enzymes and enzymatic reactions. NMR has applications for developing treatments for strokes or heart attacks, since it allows scientists to examine the biological chain reactions that occur during a heart attack or stroke.
Jordan’s laboratory at Rutgers also is working to analyze how specific bacterial enzymes work in order to develop drugs for treating diseases such as tuberculosis. Once scientists understand these enzymatic reactions, they can try to develop drugs that can halt them. “We hope that this may help us to develop new methods for creating anti-bacterial compounds that enable us to kill bacteria without killing the host,” says Jordan. Jordan’s recent studies are also directed to development of novel drugs for the treatment of diabetes.
Jordan holds three patents, has written or co-authored more than 215 journal articles and reviews, and has graduated 55 Ph.D.’s from his laboratories. He is a member of the American Chemical Society, the American Society for Biochemistry and Molecular Biology, and is an elected Fellow of the American Association for the Advancement of Science.
Jordan’s research has been supported for 35 years by the National Institutes of Health and/or the National Science Foundation.
Jordan earned his B.S. from Drexel University and the Ph.D. at the University of Pennsylvania, and completed postdoctoral fellowships at the Sorbonne in Paris and Harvard University before joining the faculty at Rutgers-Newark in 1970.